Article
Therapy failure resulting from superinfection by a drug-resistant HIV variant.
Antiviral therapy - 1 Jan 2012
Pingen Marieke, Nouwen Jan L, Dinant Sander, Albert Jan, Mild Mattias, Brodin Johanna, Simen Birgitte B, Walsh Susan, Kayser Manfred, van der Ende Marchina E, Schutten Martin, Boucher Charles A B
Abstract excerpt
BACKGROUND: HIV-1-infected patients can be superinfected with additional HIV-1 variants. Therapy failure can be the consequence of an infection with a resistant strain. METHODS: A patient was diagnosed with a recent HIV-1 infection in April 2005 and subsequently clinically monitored. HIV-1 evolution was studied by population sequencing of the first 984 bases of the pol gene as well as 454 ultra-deep...
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