Article
Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk.
Atherosclerosis - 1 Sept 2012
Camacho Mercedes, Martinez-Perez Angel, Buil Alfonso, Siguero Laura, Alcolea Sonia, López Sonia, Fontcuberta Jordi, Souto Juan-Carlos, Vila Luis, Soria José-Manuel
Abstract excerpt
OBJECTIVE: Leukotrienes (LT) play a role in inflammation, cardiovascular diseases, and cancer. Although some studies suggest that there are genes that determine variability of some LT-related phenotypes, the genetic influence on these phenotypes has not been evaluated. METHODS: The relative contributions of genetic and environmental influences to the 5-lipoxygenase pathway-related phenotypes (5-Lipoxygenase, five...
Topics
- 5-Lipoxygenase-Activating Proteins
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Arachidonate 5-Lipoxygenase
- Cardiovascular Diseases
- Child
- Child, Preschool
- Epoxide Hydrolases
- Female
- Genetic Predisposition to Disease
- Glutathione Transferase