Article
Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk.
Atherosclerosis - 1 Sept 2012
Camacho Mercedes, Martinez-Perez Angel, Buil Alfonso, Siguero Laura, Alcolea Sonia, López Sonia, Fontcuberta Jordi, Souto Juan-Carlos, Vila Luis, Soria José-Manuel
Abstract excerpt
OBJECTIVE: Leukotrienes (LT) play a role in inflammation, cardiovascular diseases, and cancer. Although some studies suggest that there are genes that determine variability of some LT-related phenotypes, the genetic influence on these phenotypes has not been evaluated. METHODS: The relative contributions of genetic and environmental influences to the 5-lipoxygenase pathway-related phenotypes (5-Lipoxygenase, five...
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