Article
Heritability of thromboxane A2 and prostaglandin E2 biosynthetic machinery in a Spanish population.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2010
Vila Luis, Martinez-Perez Angel, Camacho Mercedes, Buil Alfonso, Alcolea Sonia, Pujol-Moix Nuria, Soler Marta, Antón Rosa, Souto Juan-Carlos, Fontcuberta Jordi, Soria José-Manuel
Abstract excerpt
OBJECTIVE: Prostanoids play a critical role in clinical areas such as inflammation, thrombosis, immune response, and cancer. Although some studies suggest that there are genes that determine variability of some prostanoid-related phenotypes, the genetic influence on these traits has not been evaluated. METHODS AND RESULTS: The relative contributions of genetic and environmental influences to the prostanoid...
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