PCLO rs2522833 impacts HPA system activity in healthy young adults.

doi:10.1038/tp.2011.11

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Article

PCLO rs2522833 impacts HPA system activity in healthy young adults.

Translational psychiatry - 31 May 2011

Kuehner C, Huffziger S, Witt S H, Rietschel M

Abstract excerpt

Recent genetic studies showed evidence for a role of the single-nucleotide polymorphism rs2522833 within the PCLO gene in the etiology of major depression, and rs2522833 has been shown to modulate hypothalamic pituitary adrenal (HPA) axis activity during antidepressant treatment. Monoaminergic mo...

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Identifiers

PMID: 22832399
DOI: 10.1038/tp.2011.11
PMCID: PMC3309480

Genes

PCLO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22832399-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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