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Article

Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach.

Psychoneuroendocrinology - 1 Aug 2011

Velders Fleur P, Kuningas Maris, Kumari Meena, Dekker Marieke J, Uitterlinden Andre G, Kirschbaum Clemens, Hek Karin, Hofman Albert, Verhulst Frank C, Kivimaki Mika, Van Duijn Cornelia M, Walker Brian R, Tiemeier Henning

Abstract excerpt

BACKGROUND: Depressive patients often have altered cortisol secretion, but few studies have investigated genetic variants in relation to both cortisol secretion and depression. To identify genes related to both these conditions, we: (1) tested the association of single nucleotide polymorphisms (SNPs) in hypothalamic-pituitary-adrenal-axis (HPA-axis) candidate genes with a summary measure of total cortisol...

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Identifiers

PMID: 21316860
DOI: 10.1016/j.psyneuen.2011.01.003
PMCID: PMC3940151

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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