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Article

An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data.

Retrovirology - 25 Jul 2012

Bozek Katarzyna, Eckhardt Manon, Sierra Saleta, Anders Maria, Kaiser Rolf, Kräusslich Hans-Georg, Müller Barbara, Lengauer Thomas

Abstract excerpt

BACKGROUND: Entry of human immunodeficiency virus type 1 (HIV-1) into the host cell involves interactions between the viral envelope glycoproteins (Env) and the cellular receptor CD4 as well as a coreceptor molecule (most importantly CCR5 or CXCR4). Viral preference for a specific coreceptor (tropism) is in particular determined by the third variable loop (V3) of the Env glycoprotein gp120. The approval and use...

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Source

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Identifiers

PMID: 22830600
DOI: 10.1186/1742-4690-9-60
PMCID: PMC3464718

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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