Article
An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data.
Retrovirology - 25 Jul 2012
Bozek Katarzyna, Eckhardt Manon, Sierra Saleta, Anders Maria, Kaiser Rolf, Kräusslich Hans-Georg, Müller Barbara, Lengauer Thomas
Abstract excerpt
BACKGROUND: Entry of human immunodeficiency virus type 1 (HIV-1) into the host cell involves interactions between the viral envelope glycoproteins (Env) and the cellular receptor CD4 as well as a coreceptor molecule (most importantly CCR5 or CXCR4). Viral preference for a specific coreceptor (tro...
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