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Article

Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies.

Retrovirology - 23 Jun 2014

Chikere Kelechi, Webb Nicholas E, Chou Tom, Borm Katharina, Sterjovski Jasminka, Gorry Paul R, Lee Benhur

Abstract excerpt

BACKGROUND: The efficiency of CD4/CCR5 mediated HIV-1 entry has important implications for pathogenesis and transmission. The HIV-1 receptor affinity profiling (Affinofile) system analyzes and quantifies the infectivity of HIV-1 envelopes (Envs) across a spectrum of CD4/CCR5 expression levels and distills these data into a set of Affinofile metrics. The Affinofile system has shed light on how differential...

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Share to Antibodies, Neutralizing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, CCR5

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Source

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Identifiers

PMID: 24957778
DOI: 10.1186/1742-4690-11-48
PMCID: PMC4230403

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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