Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NLRP1, PTPN22 and PADI4 gene polymorphisms and rheumatoid arthritis in ACPA-positive Singaporean Chinese.

Rheumatology international - 1 Aug 2017

Goh Liuh Ling, Yong Mei Yun, See Wei Qiang, Chee Edward Yu Wing, Lim Pei Qi, Koh Ee Tzun, Leong Khai Pang

Abstract excerpt

Studies have shown that the genetic risk factors for rheumatoid arthritis (RA) differ substantially between Asian and Caucasian populations. Even among Asian populations, the genetic contributions of NLRP1, PTPN22 and PADI4 have been controversial. Consequently, we sought to address these separate findings and determine whether any of these proposed risk variants are associated with RA susceptibility, onset, DAS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis Regulatory Proteins
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

Share to NLR Proteins

Share to Protein-Arginine Deiminase Type 4

Share to Protein-Arginine Deiminases

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Real-Time Polymerase Chain Reaction

Source

Identifiers

PMID: 28653215
DOI: 10.1007/s00296-017-3762-x

Genes

NLRP1
PADI4
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NLRP1, PTPN22 and PADI4 gene polymorphisms and rheumatoid arthritis in ACPA-positive Singaporean Chinese.PMID 28653215Read ↗

Association of PTPN22 and PADI4 Polymorphisms with Rheumatoid Arthritis in AswanSemantic proximity Read ↗

Association between the NLRP3 rs10157379 and rs10754558 genetic variants with rheumatoid arthritis activity, autoantibodies, and inflammatory biomarkersSemantic proximity Read ↗

PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking.Semantic proximity Read ↗

NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han chinese.Semantic proximity Read ↗

A replication study confirms the association of dendritic cell immunoreceptor (DCIR) polymorphisms with ACPA - negative RA in a large Asian cohort.Semantic proximity Read ↗

Association of MiRNA-146a, MiRNA-499, IRAK1 and PADI4 Polymorphisms with Rheumatoid Arthritis in Egyptian Population.Semantic proximity Read ↗

PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study.Semantic proximity Read ↗

Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking.Semantic proximity Read ↗

Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.Semantic proximity Read ↗

CD28 and PTPN22 are associated with susceptibility to rheumatoid arthritis in Egyptians.Semantic proximity Read ↗

Association between PADI4 gene polymorphisms and anti-cyclic citrullinated peptide antibody positive rheumatoid arthritis in a large Chinese Han cohort.Semantic proximity Read ↗

Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.