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Article

Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.

Nature communications - 7 Mar 2017

Bartell Jennifer A, Blazier Anna S, Yen Phillip, Thøgersen Juliane C, Jelsbak Lars, Goldberg Joanna B, Papin Jason A

Abstract excerpt

Virulence-linked pathways in opportunistic pathogens are putative therapeutic targets that may be associated with less potential for resistance than targets in growth-essential pathways. However, efficacy of virulence-linked targets may be affected by the contribution of virulence-related genes to metabolism. We evaluate the complex interrelationships between growth and virulence-linked pathways using a...

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Identifiers

PMID: 28266498
DOI: 10.1038/ncomms14631
PMCID: PMC5344303

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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