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Article

Modulation of paraoxonases during infectious diseases and its potential impact on atherosclerosis

23 Jul 2012

Abstract excerpt

The paraoxonase (PON) gene family includes three members, PON1, PON2 and PON3, aligned in tandem on chromosome 7 in humans and on chromosome 6 in mice. All PON proteins share considerable structural homology and have the capacity to protect cells from oxidative stress; therefore, they have been implicated in the pathogenesis of several inflammatory diseases, particularly atherosclerosis. The major goal of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22824324
DOI: 10.1186/1476-511x-11-92

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