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Article

Paraoxonase 1 (PON1) reduces macrophage inflammatory responses.

Atherosclerosis - 1 Jun 2013

Aharoni Saar, Aviram Michael, Fuhrman Bianca

Abstract excerpt

OBJECTIVES: Paraoxonase 1 (PON1) was suggested to play an anti-inflammatory role. In the present study we questioned whether PON1 has a direct impact on macrophage inflammatory responses, and the possible functional implications of such effects. METHODS AND RESULTS: Ex-vivo studies were performed with bone marrow-derived macrophages (BMDM) harvested from C57BL/6 and human-PON1 transgenic (PON1-Tg) mice, and for...

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Source

Identifiers

PMID: 23582715
DOI: 10.1016/j.atherosclerosis.2013.03.005

Genes

PON1
ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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