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Article

The paraoxonase gene family and atherosclerosis.

Free radical biology & medicine - 15 Jan 2005

Ng Carey J, Shih Diana M, Hama Susan Y, Villa Natividad, Navab Mohamad, Reddy Srinivasa T

Abstract excerpt

Epidemiologic, genetic, and biochemical studies support an antiatherogenic role for paraoxonase (PON) 1. While the precise mechanism by which PON1 protects against the development of atherosclerosis is unclear, in vitro studies and the results from PON1 knockout and transgenic mice suggest that this protective effect may be attributed to PON1's ability to attenuate the oxidative modification of lipoprotein...

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Source

Identifiers

PMID: 15607899
DOI: 10.1016/j.freeradbiomed.2004.09.035

Genes

PON1
PON2
PON3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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