Article
Three single nucleotide variants of the SIRT1 gene are associated with overweight in a Chinese population: a case control study.
Endocrine journal - 1 Jan 2012
Zheng Juan, Chen Lu-Lu, Xiao Fangxi, Hu Xiang, Deng Xiulin, Li Huiqing
Abstract excerpt
We aimed to explore whether common allelic variations in the SIRT1 gene were associated with excess body weight in a Chinese cohort. Using standard molecular techniques 820 non-diabetic individuals, some of who were classified as overweight (> 23 Kg/m(2)), were genotyped for four haplotype-tagged single nucleotide polymorphisms. The rs10509291AA and rs10823116GG genotypes were associated with high body mass...
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