Article
The rebel angel: mutant p53 as the driving oncogene in breast cancer.
Carcinogenesis - 1 Nov 2012
Walerych Dawid, Napoli Marco, Collavin Licio, Del Sal Giannino
Abstract excerpt
Breast cancer is the most frequent invasive tumor diagnosed in women, causing over 400 000 deaths yearly worldwide. Like other tumors, it is a disease with a complex, heterogeneous genetic and biochemical background. No single genomic or metabolic condition can be regarded as decisive for its formation and progression. However, a few key players can be pointed out and among them is the TP53 tumor suppressor gene,...
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