Article
The Père David's deer MHC class I genes show unexpected diversity patterns, with monomorphic classical genes but polymorphic nonclassical genes and pseudogenes.
Journal of experimental zoology. Part B, Molecular and developmental evolution - 1 Jun 2012
Zhang Pei, Kuang Ye-Ye, Wu Hai-Long, Li Ling, Ge Yun-Fa, Wan Qiu-Hong, Fang Sheng-Guo
Abstract excerpt
Père David's deer (Elaphurus davidianus) is a highly inbred species that arose from 11 founders but now comprises a population of about 3,000 individuals, making it interesting to investigate the adaptive variation of this species from the major histocompatibility complex (MHC) perspective. In this study, we isolated Elda-MHC class I loci using magnetic bead-based cDNA hybridization, and examined the molecular...
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