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Article

The role of MAPT sequence variation in mechanisms of disease susceptibility.

Biochemical Society transactions - 1 Aug 2012

Caffrey Tara M, Wade-Martins Richard

Abstract excerpt

The microtubule-associated protein tau (MAPT or tau) is of great interest in the field of neurodegeneration as there is a well-established genetic link between the MAPT gene locus and tauopathies, a diverse group of neurodegenerative dementias and movement disorders. The genomic architecture in the region spanning the MAPT locus contains a ~1.8 Mb block of linkage disequilibrium characterized by two major...

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Source

Identifiers

PMID: 22817717
DOI: 10.1042/BST20120063

Genes

MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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