Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Untangling the tau gene association with neurodegenerative disorders

20 Sept 2006

Abstract excerpt

Pathological tau protein inclusions have long been recognized to define the diverse range of neurodegenerative disorders called the tauopathies, which include Alzheimer's disease (AD), progressive supranuclear palsy (PSP) and frontotemporal lobar degeneration. Mutations in the tau gene, MAPT, cause familial frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17), and common variation in MAPT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16987883
DOI: 10.1093/hmg/ddl190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Untangling the tau gene association with neurodegenerative disordersPMID 16987883Read ↗

Disentangling the role of the tau gene locus in sporadic tauopathies.Semantic proximity Read ↗

The role of MAPT sequence variation in mechanisms of disease susceptibility.Semantic proximity Read ↗

The Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and Therapy.Semantic proximity Read ↗

Tau and MAPT genetics in tauopathies and synucleinopathies.Semantic proximity Read ↗

Meta-analysis of the association between variants in MAPT and neurodegenerative diseases.Semantic proximity Read ↗

The structure of the tau haplotype in controls and in progressive supranuclear palsy.Semantic proximity Read ↗

The role of tau (MAPT) in frontotemporal dementia and related tauopathies.Semantic proximity Read ↗

Frontotemporal dementia and parkinsonism linked to chromosome 17.Semantic proximity Read ↗

Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.Semantic proximity Read ↗

[Clinical, pathological, and genetic characteristics of frontotemporal dementia and parkinsonism linked to chromosome 17 with mutations in the MAPT and PGRN].Semantic proximity Read ↗

A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17.Semantic proximity Read ↗

Genetic bases of Progressive Supranuclear Palsy: the MAPT tau disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.