Article
Association Between Polymorphisms of IL-23/IL-17 Pathway and Clinical Phenotypes of Autoimmune Thyroid Diseases.
Iranian journal of immunology : IJI - 1 Jun 2022
Cai Tiantian, Wang Guofei, Yang Yanping, Mu Kaida, Zhang Jing, Jiang Yanfei, Zhang Jin-An
Abstract excerpt
BACKGROUND: Several autoimmune and inflammatory disorders, including autoimmune thyroid diseases (AITD), have been linked to Th17 cells and the IL-23/IL-17 axis. Current data suggest that genetic variation contributes greatly to disease susceptibility to AITD. OBJECTIVES: To study the role of single nucleotide polymorphisms (SNPs) of IL-23/IL-17 pathway in AITD predisposition and test the gene-gene/gene-sex...
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