Article
Association between polymorphisms in cytokine genes IL-17A and IL-17F and development of allergic rhinitis and comorbid asthma in Chinese subjects.
Human immunology - 1 Jun 2012
Wang Min, Zhang Yuan, Han Demin, Zhang Luo
Abstract excerpt
BACKGROUND: Th17 cell lineage, a distinct pro-inflammatory lineage characterized by preferential synthesis of cytokines IL-17A and IL-17F, is thought to play an important role in the pathogenesis of allergic rhinitis (AR). OBJECTIVES: Our aim was to investigate whether polymorphisms in and around IL-17A and IL-17F genes are associated with AR and comorbid asthma. METHODS: A case-control comparison was performed...
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