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Article

Pathogenic role of Th17 cells in autoimmune thyroid disease and their underlying mechanisms.

Best practice & research. Clinical endocrinology & metabolism - 1 Mar 2023

Wang Yi, Fang Sijie, Zhou Huifang

Abstract excerpt

Autoimmune thyroid disease, encompassing Graves' disease and Hashimoto's thyroiditis, has a very complex etiology. Pathogenesis of the disease involves both genetic susceptibility and environmental triggers. Traditionally, imbalance of T helper cell 1 and 2 was thought to result in the immune disorders in Graves' disease and Hashimoto's thyroiditis. However, increasing evidence recently revealed the important...

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PMID: 36841747
DOI: 10.1016/j.beem.2023.101743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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