Serum IL-17A concentration and a IL17RA single nucleotide polymorphism contribute to the risk of autoimmune type 1 diabetes.

doi:10.1002/dmrr.3547

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Article

Serum IL-17A concentration and a IL17RA single nucleotide polymorphism contribute to the risk of autoimmune type 1 diabetes.

Diabetes/metabolism research and reviews - 1 Sept 2022

Li Junxian, Xu Lei, Zhao Weijing, Pan Jiemin, Lu Junxi, Lu Huijuan, Yan Jinhua, Weng Jianping, Liu Fang

Abstract excerpt

AIMS: Interleukin (IL)-17 is associated with autoimmunity. This study aimed to affirm the role of IL-17A, IL-17F and single nucleotide polymorphisms (SNPs) in genes related to them and their receptors in autoimmune type 1 diabetes (T1D) for Chinese population. METHODS: In this study, 130 patients with autoimmune T1D and 140 non-T1D controls were included for analysis. Clinical and biochemical data were collected,...

Topics

Case-Control Studies
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-17
Interleukin-6
Polymorphism, Single Nucleotide
Receptors, Interleukin-17

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Open in PubMed

Identifiers

PMID: 35583128
DOI: 10.1002/dmrr.3547

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