Article
Serum IL-17A concentration and a IL17RA single nucleotide polymorphism contribute to the risk of autoimmune type 1 diabetes.
Diabetes/metabolism research and reviews - 1 Sept 2022
Li Junxian, Xu Lei, Zhao Weijing, Pan Jiemin, Lu Junxi, Lu Huijuan, Yan Jinhua, Weng Jianping, Liu Fang
Abstract excerpt
AIMS: Interleukin (IL)-17 is associated with autoimmunity. This study aimed to affirm the role of IL-17A, IL-17F and single nucleotide polymorphisms (SNPs) in genes related to them and their receptors in autoimmune type 1 diabetes (T1D) for Chinese population. METHODS: In this study, 130 patients with autoimmune T1D and 140 non-T1D controls were included for analysis. Clinical and biochemical data were collected,...
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