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Article

Systematic functional characterization of cytochrome P450 2E1 promoter variants in the Chinese Han population.

PloS one - 1 Jan 2012

Huang Xunyi, Chen Lili, Song Wenlong, Chen Ling, Niu Jiamin, Han Xia, Feng Guoyin, He Lin, Qin Shengying

Abstract excerpt

CYP2E1 promoter polymorphisms can lead to significant interindividual differences in expression of CYP2E1. Using a database of CYP2E1 gene polymorphisms established in 2010, our study aimed to functionally characterize the single nucleotide polymorphisms (SNPs) of the promoter region and corresponding haplotypes in the Chinese Han population. Six novel SNPs and seven haplotypes with a frequency equal to or...

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Identifiers

PMID: 22815852
DOI: 10.1371/journal.pone.0040883
PMCID: PMC3398937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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