Article
Systematic functional study of cytochrome P450 2D6 promoter polymorphisms in the Chinese Han population.
PloS one - 1 Jan 2013
Gong Xueli, Liu Yichen, Zhang Xiaoqing, Wei Zhiyun, Huo Ran, Shen Lu, He Lin, Qin Shengying
Abstract excerpt
The promoter polymorphisms of drug-metabolizing genes can lead to interindividual differences in gene expression, which may result in adverse drug effects and therapeutic failure. Based on the database of CYP2D6 gene polymorphisms in the Chinese Han population established by our group, we functio...
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