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Article

Using rigidity analysis to probe mutation-induced structural changes in proteins.

Journal of bioinformatics and computational biology - 1 Jun 2012

Jagodzinski Filip, Hardy Jeanne, Streinu Ileana

Abstract excerpt

Predicting the effect of a single amino acid substitution on the stability of a protein structure is a fundamental task in macromolecular modeling. It has relevance to drug design and understanding of disease-causing protein variants. We present KINARI-Mutagen, a web server for performing in sili...

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PMID: 22809386
DOI: 10.1142/S0219720012420103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22809386-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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