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Article

SDM--a server for predicting effects of mutations on protein stability and malfunction.

Nucleic acids research - 1 Jul 2011

Worth Catherine L, Preissner Robert, Blundell Tom L

Abstract excerpt

The sheer volume of non-synonymous single nucleotide polymorphisms that have been generated in recent years from projects such as the Human Genome Project, the HapMap Project and Genome-Wide Association Studies means that it is not possible to characterize all mutations experimentally on the gene products, i.e. elucidate the effects of mutations on protein structure and function. However, automatic methods that...

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Identifiers

PMID: 21593128
DOI: 10.1093/nar/gkr363
PMCID: PMC3125769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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