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Article

Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice.

Physiological genomics - 1 Sept 2012

Wiltshire Sean A, Diez Eduardo, Miao Qianqian, Dubé Marie-Pierre, Gagné Mireille, Paquette Olivier, Lafrenière Ronald G, Ndao Momar, Castellani Lawrence W, Skamene Emil, Vidal Silvia M, Fortin Anny

Abstract excerpt

Epidemiological studies show that high HDL-cholesterol (HDLc) decreases the risk of cardiovascular disease. To map genes controlling lipid metabolism, particularly HDLc levels, we screened the plasma lipids of 36 AcB/BcA RC mouse strains subjected to either a normal or a high-fat/cholesterol diet. Strains BcA68 and AcB65 showed deviant HDLc plasma levels compared with the parental A/J and C57BL/6J strains; they...

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Share to Apolipoprotein A-I
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Diet, High-Fat

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Share to Mice, Inbred C57BL

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Source

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Identifiers

PMID: 22805347
DOI: 10.1152/physiolgenomics.00025.2012
PMCID: PMC3888445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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