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Quantitative trait locus mapping of genes that regulate HDL cholesterol in SM/J and NZB/B1NJ inbred mice.

Physiological genomics - 1 Jan 2002

Pitman Wendy A, Korstanje Ron, Churchill Gary A, Nicodeme Edwige, Albers John J, Cheung Marian C, Staton Megan A, Sampson Stephen S, Harris Stephen, Paigen Beverly

Abstract excerpt

To investigate the quantitative trait loci (QTL) regulating plasma cholesterol, the female progeny of an (SMxNZB/ B1NJ)xNZB/B1NJ backcross were fed an atherogenic diet. After 18 wk, plasma total cholesterol and high-density lipoprotein cholesterol (HDL-C) was measured. HDL-C concentrations were greater in NZB than in SM mice. For standard chow-fed mice, QTL were found near D5Mit370 and D18Mit34. For mice fed an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins, HDL

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Share to Receptors, Lipoprotein

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Identifiers

PMID: 12006675
DOI: 10.1152/physiolgenomics.00107.2001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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