Article
A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.
Journal of lipid research - 1 Apr 2000
Mouzeyan A, Choi J, Allayee H, Wang X, Sinsheimer J, Phan J, Castellani L W, Reue K, Lusis A J, Davis R C
Abstract excerpt
Dietary cholesterol is known to raise total and low density lipoprotein cholesterol concentrations in humans and experimental animals, but the response among individuals varies greatly. Here we describe a mouse strain, C57BL/6ByJ (B6By), that is resistant to diet-induced hypercholesterolemia, in contrast to the phenotype seen in other common strains of mice including the closely related C57BL/6J (B6J) strain....
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