Article
Pocketcheck: updating the HLA class I peptide specificity roadmap.
Tissue antigens - 1 Sept 2012
Huyton T, Ladas N, Schumacher H, Blasczyk R, Bade-Doeding C
Abstract excerpt
The structural determination of peptide:HLA (human leucocyte antigen) class I complexes by X-ray crystallography has provided valuable information for understanding how peptides bind to individual HLA class I molecules and how this may influence the immune response. We compared 101 crystal structures of 9-mer peptide:HLA class I complexes available in the protein data bank (PDB) by performing a contact analysis...
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