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Article

Hematopoietic stem cell development requires transient Wnt/β-catenin activity.

The Journal of experimental medicine - 30 Jul 2012

Ruiz-Herguido Cristina, Guiu Jordi, D'Altri Teresa, Inglés-Esteve Julia, Dzierzak Elaine, Espinosa Lluis, Bigas Anna

Abstract excerpt

Understanding how hematopoietic stem cells (HSCs) are generated and the signals that control this process is a crucial issue for regenerative medicine applications that require in vitro production of HSC. HSCs emerge during embryonic life from an endothelial-like cell population that resides in t...

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Identifiers

PMID: 22802352
DOI: 10.1084/jem.20120225
PMCID: PMC3409499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22802352-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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