Article
CD4+ and CD8+ T-cell skewness in classic Kaposi sarcoma.
Neoplasia (New York, N.Y.) - 1 Jun 2012
Galleu Antonio, Fozza Claudio, Simula Maria Pina, Contini Salvatore, Virdis Patrizia, Corda Giovanna, Pardini Simonetta, Cottoni Francesca, Pruneddu Sara, Angeloni Antonio, Ceccarelli Simona, Longinotti Maurizio
Abstract excerpt
It is widely accepted that a deranged immune system plays a key role in the onset and evolution of classic Kaposi sarcoma (CKS). Nevertheless, the usage of the T-cell receptor (TCR) β-variable (BV) chain repertoire expressed by peripheral blood lymphocytes in patients with CKS is still unknown. With the aim of providing some further insights into the complex role of the immune system in CKS pathogenesis, we...
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