Cytotoxic T cells targeting lytic KSHV gene products infiltrate Kaposi sarcoma tumors

Abstract excerpt

Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and KSHV-associated multicentric Castleman’s disease (MCD), malignancies that predominantly arise in the context of T-cell deficiency. Unlike responses to other human herpesviruses such as EBV and CMV, KSHV-specific T-cell responses detected in blood have been described as heterogeneous and...

Topics

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• Cluster Analysis
• Clustering Algorithms
• Cytomegalovirus and herpesvirus research
• Herpesvirus 8, Human
• Herpesvirus Infections and Treatments
• Immune Cell Function and Interaction
• Lymphoma Diagnosis and Treatment
• Viral-associated cancers and disorders

Identifiers and source

Literature Corpus work

e7ab563e-9894-5816-93e6-440e52725870

DOI

10.64898/2026.06.05.730414