Article
DAPK1 is associated with FTD and not with Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2012
Tedde Andrea, Piaceri Irene, Bagnoli Silvia, Lucenteforte Ersilia, Piacentini Silvia, Sorbi Sandro, Nacmias Benedetta
Abstract excerpt
Apoptosis is correlated with various forms of dementia. Death-associated protein kinase 1 (DAPK1) plays an important role in neuronal apoptosis and could influence the pathology of late-onset Alzheimer's disease (LOAD) and frontotemporal dementia (FTD). It has been reported that two common polymorphisms (rs4878104 and rs4877365) are associated with LOAD, thus we examined the genotype and allele distributions of...
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