Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DAPK1: a Novel Pathology and Treatment Target for Alzheimer's Disease.

Molecular neurobiology - 1 Apr 2019

Xu Ling-Zhi, Li Bing-Qiu, Jia Jian-Ping

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disease and seriously damages the health of elderly population. Clinical drug research targeting at classic pathology hallmarks, such as amyloid-β (Aβ) and tau protein, failed to achieve effective cognitive improvement, suggesting that the pathogenesis of AD is much complicated, and there are still other unknown and undetermined important factors....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Biomarkers
Share to Death-Associated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Molecular Targeted Therapy

Share to Risk Factors

Source

Identifiers

PMID: 30062675
DOI: 10.1007/s12035-018-1242-2

Genes

DAPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DAPK1: a Novel Pathology and Treatment Target for Alzheimer's Disease.PMID 30062675Read ↗

Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function.Semantic proximity Read ↗

Rs4878104 contributes to Alzheimer's disease risk and regulates DAPK1 gene expression.Semantic proximity Read ↗

Association of DAPK1 genetic variations with Alzheimer's disease in Han Chinese.Semantic proximity Read ↗

The Death-Associated Protein Kinases: Structure, Function, and BeyondSemantic proximity Read ↗

Potential Implications of miRNAs in the Pathogenesis, Diagnosis, and Therapeutics of Alzheimer’s DiseaseSemantic proximity Read ↗

The role of UNC5C in Alzheimer’s diseaseSemantic proximity Read ↗

Integrated Bioinformatics Analysis Identifies Pyroptosis-related Genes in Alzheimer’s DiseaseSemantic proximity Read ↗

The study on cuproptosis in Alzheimer’s disease based on the cuproptosis key gene FDX1Semantic proximity Read ↗

A Diagnostic Model for Alzheimer’s Disease Based on Blood Levels of Autophagy-Related GenesSemantic proximity Read ↗

MicroRNA-26a/Death-Associated Protein Kinase 1 Signaling Induces Synucleinopathy and Dopaminergic Neuron Degeneration in Parkinson’s DiseaseSemantic proximity Read ↗

Multiomics Identification of Potential Targets for Alzheimer Disease and Antrocin as a Therapeutic CandidateSemantic proximity Read ↗

DYRK1A Inhibitors and Perspectives for the Treatment of Alzheimer's DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.