Article
Common variant in PTK2B is associated with late-onset Alzheimer's disease: A replication study and meta-analyses.
Neuroscience letters - 16 May 2016
Li Ya-Qing, Tan Meng-Shan, Wang Hui-Fu, Tan Chen-Chen, Zhang Wei, Zheng Zhan-Jie, Kong Ling-Li, Wang Zi-Xuan, Tan Lin, Jiang Teng, Tan Lan, Yu Jin-Tai
Abstract excerpt
Emerging evidence indicates that protein tyrosine kinase 2β (PTK2B) is involved in the pathogenesis of Alzheimer's disease (AD). Recently, a large, two-stage meta-analysis of genome-wide association study (GWAS) confirmed that PTK2B was correlated with an increased risk of AD in Caucasian populations. The aim of this study was to investigate the association between PTK2B polymorphism rs28834970 and the risk of...
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