Article
Use of a high resolution melting assay to analyze HIV diversity in HIV-infected Ugandan children.
The Pediatric infectious disease journal - 1 Nov 2012
James Maria M, Wang Lei, Donnell Deborah, Cousins Matthew M, Barlow-Mosha Linda, Fogel Jessica M, Towler William I, Agwu Allison L, Bagenda Danstan, Mubiru Micheal, Musoke Philippa, Eshleman Susan H
Abstract excerpt
BACKGROUND: We used a novel high resolution melting (HRM) diversity assay to analyze HIV diversity in Ugandan children (age 0.6-12.4 years) who were enrolled in an observational study of antiretroviral treatment (ART). Children were maintained on ART if they were clinically and immunologically stable. METHODS: HIV diversity was measured before ART (baseline) in 76 children and after 48 or 96 weeks of ART in 14...
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