Article
Antibody maturation and viral diversification in HIV-infected women.
PloS one - 1 Jan 2013
James Maria M, Laeyendecker Oliver, Sun Jin, Hoover Donald R, Mullis Caroline E, Cousins Matthew M, Coates Thomas, Moore Richard D, Kelen Gabor D, Fowler Mary Glenn, Kumwenda Johnstone J, Mofenson Lynne M, Kumwenda Newton I, Taha Taha E, Eshleman Susan H
Abstract excerpt
INTRODUCTION: The Post-exposure Prophylaxis in Infants (PEPI)-Malawi trial evaluated infant antiretroviral regimens for prevention of post-natal HIV transmission. A multi-assay algorithm (MAA) that includes the BED capture immunoassay, an avidity assay, CD4 cell count, and viral load was used to identify women who were vs. were not recently infected at the time of enrollment (MAA recent, N = 73; MAA non-recent,...
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