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Article

AID targeting is dependent on RNA polymerase II pausing.

Seminars in immunology - 1 Aug 2012

Kenter Amy L

Abstract excerpt

Activation induced deaminase (AID) is globally targeted to immunoglobulin loci, preferentially focused to switch (S) regions and variable (V) regions, and prone to attack hotspot motifs. Nevertheless, AID deamination is not exclusive to Ig loci and the rules regulating AID targeting remain unclea...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
Share to Cytidine Deaminase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Elements, Transcriptional

Share to RNA Polymerase II

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Source

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Identifiers

PMID: 22784681
DOI: 10.1016/j.smim.2012.06.001
PMCID: PMC3630797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22784681-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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