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Article

Endoplasmic reticulum aminopeptidase 1 and interleukin-23 receptor in ankylosing spondylitis.

Current rheumatology reports - 1 Oct 2012

Haroon Nigil

Abstract excerpt

Endoplasmic reticulum aminopeptidase 1 (ERAP1) and interleukin-23 receptor (IL-23R) gene polymorphisms were found to be associated with ankylosing spondylitis (AS) in a nonsynonymous single nucleotide polymorphism association study, and this has been replicated in several studies across different populations. ERAP1 variants could lead to significant changes in the repertoire of peptides presented by MHC-I....

Read the complete abstract on PubMed

Topics

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Share to Aminopeptidases
Share to ERAP1 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B27 Antigen

Share to Minor Histocompatibility Antigens

Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin

Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 22782541
DOI: 10.1007/s11926-012-0268-0

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Endoplasmic reticulum aminopeptidase 1 and interleukin-23 receptor in ankylosing spondylitis.PMID 22782541Read ↗

ERAP1 and ankylosing spondylitis.Semantic proximity Read ↗

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Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis.Semantic proximity Read ↗

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Endoplasmic reticulum aminopeptidases in the pathogenesis of ankylosing spondylitis: Fig. 1Semantic proximity Read ↗

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