Article
Endoplasmic reticulum aminopeptidase 2 gene single nucleotide polymorphisms in association with susceptibility to ankylosing spondylitis in an Iranian population.
Immunology letters - 1 Jul 2020
Ebrazeh Mehrdad, Nojavan Mohammad, Abdi-Shayan Shiva, Salimifard Sevda, Dolatshahi Elahe, Aslani Saeed, Hemmatzadeh Maryam, Babaie Farhad, Ghanavatinejad Alireza, Azizi Gholamreza, Jadidi-Niaragh Farhad, Zamani Neda, Mohammadi Hamed
Abstract excerpt
BACKGROUND: Ankylosing spondylitis (AS) is a chronic autoimmune disease, in which genetic polymorphisms are critically important in establishing inflammatory state. Endoplasmic reticulum aminopeptidase (ERAP) 2 gene has been implied to be involved in AS etiopathogenesis. The current study evaluated the association of ERAP2 gene single nucleotide polymorphisms (SNPs) with susceptibility to AS in an Iranian...
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