Article
Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series.
Rheumatology (Oxford, England) - 1 Apr 2009
Karaderi Tugce, Harvey David, Farrar Claire, Appleton Louise H, Stone Millicent A, Sturrock Roger D, Brown Matthew A, Wordsworth Paul, Pointon Jennifer J
Abstract excerpt
OBJECTIVES: It has been shown previously that IL-23R variants are associated with AS. We conducted an extended analysis in the UK population and a meta-analysis with the previously published studies, in order to refine these IL-23R associations with AS. METHODS: The UK case-control study included 730 new cases and 1331 healthy controls. In the extended study, the 730 cases were combined with 1088 published cases....
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