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Article

Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy.

The Journal of biological chemistry - 24 May 2013

Dokladny Karol, Zuhl Micah Nathaniel, Mandell Michael, Bhattacharya Dhruva, Schneider Suzanne, Deretic Vojo, Moseley Pope Lloyd

Abstract excerpt

The eukaryotic cell depends on multitiered homeostatic systems ensuring maintenance of proteostasis, organellar integrity, function and turnover, and overall cellular viability. At the two opposite ends of the homeostatic system spectrum are heat shock response and autophagy. Here, we tested whether there are interactions between these homeostatic systems, one universally operational in all prokaryotic and...

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Identifiers

PMID: 23576438
DOI: 10.1074/jbc.M113.462408
PMCID: PMC3663517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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