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Article

Multiomic Landscape of Gastrointestinal Stromal Tumors in a Real-World Patient Cohort of 1,427 Cases.

Clinical cancer research : an official journal of the American Association for Cancer Research - 14 Aug 2026

Serrano César, Elliott Andrew, Gómez-Peregrina David, Evans Mark G, George Suzanne, von Mehren Margaret, Maki Robert G, Boikos Sosipatros A, Charlson John A, Dhir Aditi, Florou Vaia, Mahadevan Daruka, Oberley Matthew J, Sledge George W, Tinoco Gabriel, Riedel Richard F, Trent Jonathan C

Abstract excerpt

PURPOSE: Gastrointestinal stromal tumor (GIST) is a genomically driven neoplasm with a genetic profile that determines the clinical course of the disease. However, currently available molecular data are limited because of the rarity of the disease and do not fully capture GIST clinical and biological heterogeneity. EXPERIMENTAL DESIGN: To gain deeper insights into the molecular landscape of GIST, we performed a...

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Identifiers

PMID: 42059893
DOI: 10.1158/1078-0432.CCR-25-4596
PMCID: PMC13417434

Genes

KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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