Article
Molecular Profile of Gastrointestinal Stromal Tumors in Sixty-Eight Patients from a Single Swiss Institution.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2020
Haefliger Simon, Marston Katharina, Juskevicius Darius, Meyer-Schaller Nathalie, Forster Anja, Nicolet Stefan, Komminoth Paul, Stauffer Edouard, Cathomas Gieri, Hoeller Sylvia, Tornillo Luigi, Dirnhofer Stefan, Terracciano Luigi M, Bihl Michel, Matter Matthias S
Abstract excerpt
INTRODUCTION: Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract. It has distinct molecular features and primarily affects the KIT and PDGFRA genes. OBJECTIVE: We wanted to assess the molecular profile of 68 GIST patients who were sequenced consecutively between 2014 and 2019 at our institute of pathology. METHODS: Our cohort comprised 60 primary and 8...
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