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Article

Impact of schizophrenia-risk gene dysbindin 1 on brain activation in bilateral middle frontal gyrus during a working memory task in healthy individuals.

Human brain mapping - 1 Feb 2010

Markov Valentin, Krug Axel, Krach Sören, Jansen Andreas, Eggermann Thomas, Zerres Karl, Stöcker Tony, Shah N Jon, Nöthen Markus M, Treutlein Jens, Rietschel Marcella, Kircher Tilo

Abstract excerpt

Working memory (WM) dysfunction is a hallmark feature of schizophrenia. Functional imaging studies using WM tasks have documented both prefrontal hypo- and hyperactivation in schizophrenia. Schizophrenia is highly heritable, and it is unclear which susceptibility genes modulate WM and its neural correlates. A strong linkage between genetic variants in the dysbindin 1 gene and schizophrenia has been demonstrated....

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Source

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Identifiers

PMID: 19650139
DOI: 10.1002/hbm.20862
PMCID: PMC6871017

Genes

DTNBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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