Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis.

PloS one - 1 Jan 2012

Derks Eske M, Vorstman Jacob A S, Ripke Stephan, Kahn Rene S, Ophoff Roel A

Abstract excerpt

The presence of subclinical levels of psychosis in the general population may imply that schizophrenia is the extreme expression of more or less continuously distributed traits in the population. In a previous study, we identified five quantitative measures of schizophrenia (positive, negative, d...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Genome, Human
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multifactorial Inheritance

Share to Netherlands

Share to Prognosis

Share to Psychotic Disorders

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 22761660
DOI: 10.1371/journal.pone.0037852
PMCID: PMC3382234

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22761660-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis.PMID 22761660Read ↗

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders.Semantic proximity Read ↗

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.Semantic proximity Read ↗

Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophreniaSemantic proximity Read ↗

The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review.Semantic proximity Read ↗

Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder.Semantic proximity Read ↗

Polygenic risk score and the psychosis continuum model.Semantic proximity Read ↗

Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four healthcare systemsSemantic proximity Read ↗

Role of 108 schizophrenia-associated loci in modulating psychopathological dimensions in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study.Semantic proximity Read ↗

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative SymptomsSemantic proximity Read ↗

Clinical characteristics indexing genetic differences in schizophrenia: a systematic review.Semantic proximity Read ↗

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.