Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.

doi:10.1176/appi.ajp.2012.12020218

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.

The American journal of psychiatry - 1 Dec 2012

Fanous Ayman H, Zhou Baiyu, Aggen Steven H, Bergen Sarah E, Amdur Richard L, Duan Jubao, Sanders Alan R, Shi Jianxin, Mowry Bryan J, Olincy Ann, Amin Farooq, Cloninger C Robert, Silverman Jeremy M, Buccola Nancy G, Byerley William F, Black Donald W, Freedman Robert, Dudbridge Frank, Holmans Peter A, Ripke Stephan, Gejman Pablo V, Kendler Kenneth S, Levinson Douglas F

Abstract excerpt

OBJECTIVE: Multiple sources of evidence suggest that genetic factors influence variation in clinical features of schizophrenia. The authors present the first genome-wide association study (GWAS) of dimensional symptom scores among individuals with schizophrenia. METHOD: Based on the Lifetime Dimensions of Psychosis Scale ratings of 2,454 case subjects of European ancestry from the Molecular Genetics of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor Analysis, Statistical

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Multifactorial Inheritance

Share to Psychiatric Status Rating Scales

Share to Schizophrenia

Share to Schizophrenic Psychology

Source

Open in PubMed Open full text

Identifiers

PMID: 23212062
DOI: 10.1176/appi.ajp.2012.12020218
PMCID: PMC3646712

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.PMID 23212062Read ↗

Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative SymptomsSemantic proximity Read ↗

Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophreniaSemantic proximity Read ↗

Polygenic signal for symptom dimensions and cognitive performance in patients with chronic schizophreniaSemantic proximity Read ↗

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis.Semantic proximity Read ↗

Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia.Semantic proximity Read ↗

Role of 108 schizophrenia-associated loci in modulating psychopathological dimensions in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Genome-wide linkage scan of quantitative traits representing symptom dimensions in multiplex schizophrenia families.Semantic proximity Read ↗

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.Semantic proximity Read ↗

Clinical characteristics indexing genetic differences in schizophrenia: a systematic review.Semantic proximity Read ↗

Genetic Basis of Positive and Negative Symptom Domains in Schizophrenia.Semantic proximity Read ↗

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders.Semantic proximity Read ↗

Pathway-based polygenic risk scores for schizophrenia and associations with clinical and neuroimaging phenotypes in UK BiobankSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.