Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme.

Nucleic acids research - 1 Oct 2012

Benjdia Alhosna, Heil Korbinian, Barends Thomas R M, Carell Thomas, Schlichting Ilme

Abstract excerpt

Bacterial spores possess an enormous resistance to ultraviolet (UV) radiation. This is largely due to a unique DNA repair enzyme, Spore Photoproduct Lyase (SP lyase) that repairs a specific UV-induced DNA lesion, the spore photoproduct (SP), through an unprecedented radical-based mechanism. Unlik...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Catalytic Domain
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to DNA Repair Enzymes

Share to Proteins

Share to S-Adenosylmethionine

Share to Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 22761404
DOI: 10.1093/nar/gks603
PMCID: PMC3467042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22761404-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme.PMID 22761404Read ↗

A radical transfer pathway in spore photoproduct lyase.Semantic proximity Read ↗

Mechanistic studies of the spore photoproduct lyase via a single cysteine mutation.Semantic proximity Read ↗

Mechanism-Based Strategies for Structural Characterization of Radical SAM Reaction Intermediates.Semantic proximity Read ↗

A structural model for the damage-sensing complex in bacterial nucleotide excision repair.Semantic proximity Read ↗

The Radical SAM Enzyme BlsE Can Operate as a Dehydratase, Dehydrogenase, or Epimerase upon Mutation of a Single Active Site Serine Residue.Semantic proximity Read ↗

Dynamics and mechanisms of DNA repair by photolyase.Semantic proximity Read ↗

The mechanism of action of DNA photolyases.Semantic proximity Read ↗

UV photochemistry of DNA in vitro and in Bacillus subtilis spores at earth-ambient and low atmospheric pressure: implications for spore survival on other planets or moons in the solar system.Semantic proximity Read ↗

Biochemical and Spectroscopic Characterization of a Radical S-Adenosyl-L-methionine Enzyme Involved in the Formation of a Peptide Thioether Cross-Link.Semantic proximity Read ↗

Crystal structure of MutYX: a novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-oxoguanine recognition sphere.Semantic proximity Read ↗

Molecular dissection of mutations in the Bacillus subtilis spore photoproduct lyase gene which affect repair of spore DNA damage caused by UV radiation.Semantic proximity Read ↗

UvrC Coordinates an O2-Sensitive [4Fe4S] Cofactor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.