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Article

A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes.

Genetic epidemiology - 1 Sept 2012

Lu Qing, Wei Changshuai, Ye Chengyin, Li Ming, Elston Robert C

Abstract excerpt

The potential importance of the joint action of genes, whether modeled with or without a statistical interaction term, has long been recognized. However, identifying such action has been a great challenge, especially when millions of genetic markers are involved. We propose a likelihood ratio-based Mann-Whitney test to search for joint gene action either among candidate genes or genome-wide. It extends the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22760990
DOI: 10.1002/gepi.21651
PMCID: PMC3634342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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