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Article

Detecting genetic interactions for quantitative traits with U-statistics.

Genetic epidemiology - 1 Sept 2011

Li Ming, Ye Chengyin, Fu Wenjiang, Elston Robert C, Lu Qing

Abstract excerpt

The genetic etiology of complex human diseases has been commonly viewed as a process that involves multiple genetic variants, environmental factors, as well as their interactions. Statistical approaches, such as the multifactor dimensionality reduction (MDR) and generalized MDR (GMDR), have recently been proposed to test the joint association of multiple genetic variants with either dichotomous or continuous...

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Identifiers

PMID: 21618602
DOI: 10.1002/gepi.20594
PMCID: PMC3575166

Genes

CHRNA5
NTRK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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